Where’s My Aspirin?

Should aspirin, acetominophen or penicillin be used? Derek Lowe argues that today not only would they not be approved by the FDA they likely would not even be submitted for approval:

The best example is aspirin itself. It’s one of the foundation stones of the drug industry, and it’s hard to even guess how many billions of doses of it have been taken over the last hundred years. But if you were somehow able to change history so that aspirin had never been discovered until this year, I can guarantee you that it would have died in the lab. No modern drug development organization would touch it.

I don’t know about you but I would be very unhappy not to have aspirin, etc., in my home arsenal and I had more than one childhood infection cleared by penicillin. On the other hand I have seen first hand the frightening experience of an allergic reaction to one of penicillin’s offspring.
I do, though, lean in the same direction as Lowe:

We can be relieved that we’ve learned so much more about pharmacology, ensuring that the drugs that manage to gain approval today are the safer than ever. Or we can think about how people seem to use aspirin and the other legacy drugs anyway, safety problems and all, and wonder how many more useful medicines we’re losing by insisting on a higher bar.
I definitely see the point of the former, but I lean a bit toward the latter.

The final informed choice on drug use should be made by a well informed patient. If the patient is being treated by a medical professional responsibility for providing the full set of information on a course of treatment belongs to the medical professional. If the patient is self-treating then the patient is responsible for acquiring the information. In both cases it is the patient who must make the final evaluation of a course of treatment.
That many people are not competent to make these evaluations and decisions is one of the great failings of our culture, our education system and our health care system.
Via Marginal Revolution.

So You Want To Be An Academic

This seems like it would be just the thing for bloggers:

I asked everyone the same question: “What’s it really like to have your job?”
Instead of responding with: “Do you like teaching?” they all asked: “Do you like to write?”

It does appear that some tenured academic bloggers have plenty of time to write. Heck, even some of the untenured ones (until recently) appear to have a lot of writing time.
But there is more to the academic life than just writing. Read the rest of the above linked article.
Via TaxProf Blog.

Don’t Say These Words…

If you haven’t checked out the video blog Rocketboom yet here is a good introduction. Several stories in, about midway through the broadcast, Amanda demonstrates an undocumented shortcut on the TI-99 which produces the 7 words you can’t say in kindergarten.
Not work friendly!! Ok, if you are wearing headphones. Oh, and ignore if you are easiy offended by language.
But pretty funny.